I think what he means is inside a data file, he has a string that says "C:\Program Files\MyApp". But if the application is installed in another location, like "D:\MyApp", the prebuilt data file will be wrong. He is wondering if there is a command to to search-and-replace inside a file that you have extracted.
The short answer is no, it can't be done. But a better answer is that yes, you can do it *but* you will have to write a program that does this yourself. I have a search-and-repace program of my own which I use, its about 15kb and runs silently, but it is so heavily dependant on my datafile structure that it would be useless to anyone else. I have a feeling that most people will find it easier to create customized programs like this than to try to find a generic solution.